The SRSF8 Polyclonal Antibody (CAB17090) is an essential tool for researchers studying SRSF8, a key splicing factor involved in RNA processing. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the SRSF8 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an excellent choice for studies in molecular biology and gene regulation.
SRSF8 is a critical player in alternative splicing, a process that generates protein diversity and regulates gene expression. Dysregulation of splicing factors like SRSF8 has been linked to various diseases, including cancer and neurological disorders. Investigating the function of SRSF8 using this antibody can provide valuable insights into the mechanisms underlying these conditions, potentially leading to the development of targeted therapeutics.
Product Name:
SRSF8 Rabbit Polyclonal Antibody
SKU:
CAB17090
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SRSF8 (NP_115285.1).
This gene encodes a member of a family of proteins containing a ribonucleoprotein (RNP)-type RNA binding motif and a carboxyl-terminal arginine-serine-rich (RS) domain. The encoded protein functions as a pre-mRNA splicing factor. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10929
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SRSF8 Rabbit pAb (CAB17090) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
