The SRSF7 Polyclonal Antibody (CAB16738) is a valuable tool for researchers studying SRSF7, a key protein involved in mRNA splicing and regulation of gene expression. This antibody, produced in rabbits, demonstrates high specificity and reactivity with human samples, making it an ideal choice for Western blot applications. By targeting the SRSF7 protein, this antibody allows for precise detection and analysis in a variety of cell types, opening up new possibilities for research in areas such as RNA biology and cancer biology.SRSF7, also known as splicing factor 1, plays a crucial role in the intricate process of pre-mRNA splicing, influencing the generation of diverse protein isoforms and impacting gene expression patterns.
Dysregulation of SRSF7 has been linked to numerous diseases, including cancer and neurological disorders, highlighting its potential as a therapeutic target. By understanding the functions and mechanisms of SRSF7, researchers can uncover novel insights into disease pathways and potentially develop targeted therapies with improved efficacy and precision.
Product Name:
SRSF7 Rabbit Polyclonal Antibody
SKU:
CAB16738
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 60-120 of human SRSF7 (NP_001026854).
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an N-terminal RNA recognition motif (RRM) for binding RNA and a C-terminal RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6432
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SRSF7 Rabbit pAb (CAB16738) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
