The SRSF6 Polyclonal Antibody (CAB14603) is a valuable tool for researchers studying SRSF6, a splicing factor protein involved in regulating gene expression and mRNA processing. This antibody, produced in rabbits, is highly specific for human samples and is suitable for Western blot applications. It binds to the SRSF6 protein, allowing for the detection and analysis of SRSF6 in a variety of cell types, making it ideal for investigations in molecular biology and cancer research.SRSF6, also known as SRp55, plays a crucial role in alternative splicing, which is essential for generating protein diversity and regulating gene expression.
Dysregulation of SRSF6 has been linked to various diseases, including cancer and neurodegenerative disorders, making it an attractive target for therapeutic intervention. By studying the function of SRSF6, researchers can gain insights into its role in disease pathogenesis and potentially identify new treatment strategies.
Product Name:
SRSF6 Rabbit Polyclonal Antibody
SKU:
CAB14603
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SRSF6 (NP_006266.2).
The protein encoded by this gene is involved in mRNA splicing and may play a role in the determination of alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12. Alternative splicing results in multiple transcript variants. In addition, two pseudogenes, one on chromosome 17 and the other on the X chromosome, have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6431
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SRSF6 Rabbit pAb (CAB14603) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
