The SRSF4 Polyclonal Antibody (CAB6978) is a valuable tool for researchers studying SRSF4, a splicing factor involved in the regulation of gene expression. This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By targeting the SRSF4 protein, this antibody enables the detection and analysis of SRSF4 levels in a variety of cell types, making it well-suited for studies in molecular biology and cancer research.SRSF4 is known to play a crucial role in alternative splicing, a process that determines the diversity of mRNA transcripts and therefore the proteins produced by a cell.
Dysregulation of alternative splicing has been linked to various diseases, including cancer and neurological disorders. By investigating the function of SRSF4, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets.In summary, the SRSF4 Polyclonal Antibody is a reliable tool for researchers interested in studying gene expression regulation and alternative splicing processes. Its specificity and sensitivity make it a valuable asset for investigations into the role of SRSF4 in disease development and progression.
Product Name:
SRSF4 Rabbit Polyclonal Antibody
SKU:
CAB6978
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human SRSF4 (NP_005617.2).
Enables RNA binding activity. Involved in negative regulation of mRNA splicing, via spliceosome. Located in nuclear speck. Biomarker of Down syndrome; acute myeloid leukemia; clear cell renal cell carcinoma; and colon adenocarcinoma.
Purification Method:
Affinity purification
Gene ID:
6429
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using SRSF4 Rabbit pAb (CAB6978) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
