The SRSF3 Polyclonal Antibody (CAB6067) is a valuable tool for researchers studying SRSF3, a member of the serine/arginine-rich splicing factor family that plays a crucial role in alternative splicing regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the SRSF3 protein, this antibody enables detection and analysis in a variety of cell types, making it ideal for studies in molecular biology, gene expression, and RNA splicing.
SRSF3 is known to be involved in the regulation of pre-mRNA splicing, influencing the production of multiple protein isoforms from a single gene. Dysregulation of alternative splicing has been linked to various diseases, including cancer and neurological disorders, highlighting the importance of studying SRSF3 function. By understanding the role of SRSF3 in splicing processes, researchers can gain insights into disease mechanisms and potentially identify novel therapeutic targets for intervention.
Product Name:
SRSF3 Rabbit Polyclonal Antibody
SKU:
CAB6067
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human SRSF3 (NP_003008.1).
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants, one protein-coding and the other non-coding, have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6428
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SRSF3 Rabbit pAb (CAB6067) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
