SRSF2 Rabbit Polyclonal Antibody (CAB3635)
- SKU:
- CAB3635
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | SRSF2 Rabbit Polyclonal Antibody |
SKU: | CAB3635 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SRSF2 (NP_001182356.1). |
Sequence: | MSYG RPPP DVEG MTSL KVDN LTYR TSPD TLRR VFEK YGRV GDVY IPRD RYTK ESRG FAFV RFHD KRDA EDAM DAMD GAVL DGRE LRVQ MARY GRPP DSHH |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | SC35; PR264; SC-35; SFRS2; SFRS2A; SRp30b; SRSF2 |
Positive Sample: | Mouse lung,Raji,THP-1 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus, Nucleus speckle, nucleoplasm. |
Calculated MW: | 25kDa |
Observed MW: | 28kDa/32kDa |
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 11.
Purification Method: | Affinity purification |
Gene ID: | 6427 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |