The SRRM1 Polyclonal Antibody (CAB6066) is a valuable tool for research involving SRRM1, a critical splicing factor involved in the regulation of alternative splicing. This antibody, produced in rabbits, exhibits high specificity and sensitivity in detecting SRRM1 in human samples, making it ideal for use in Western blot applications. By targeting the SRRM1 protein, this antibody enables researchers to analyze its expression and function in various cell types, particularly in the context of gene regulation and RNA splicing mechanisms.SRRM1 plays a crucial role in the splicing of pre-mRNA, which is essential for modulating gene expression and protein diversity. Dysregulation of SRRM1 has been implicated in various diseases, including cancer and neurodevelopmental disorders, highlighting its significance in cellular processes.
By characterizing the role of SRRM1 in splicing events, researchers can gain insights into its impact on disease pathology and potentially identify novel therapeutic targets for intervention.In summary, the SRRM1 Polyclonal Antibody (CAB6066) provides researchers with a reliable tool for investigating the function of SRRM1 in biological processes, offering valuable insights into its role in disease development and progression. Its specificity and effectiveness in detecting SRRM1 make it a valuable resource for studies in molecular biology, cancer research, and other related fields.
Product Name:
SRRM1 Rabbit Polyclonal Antibody
SKU:
CAB6066
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human SRRM1 (NP_005830.2).
Enables RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Located in nuclear speck. Part of catalytic step 2 spliceosome. Biomarker of gestational diabetes.
Purification Method:
Affinity purification
Gene ID:
10250
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SRRM1 Rabbit pAb (CAB6066) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
