The SRPRB Polyclonal Antibody (CAB10591) is a specialized tool for researchers studying SRPRB, a protein involved in protein targeting to the endoplasmic reticulum (ER) in cells. Raised in rabbits, this antibody is highly specific for human samples and has been rigorously validated for use in Western blot applications. By binding to the SRPRB protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in cell biology and protein trafficking studies.SRPRB is a crucial component in the process of protein synthesis and transport within the cell, playing a key role in ensuring that proteins are correctly targeted to the ER for proper folding and processing.
Dysregulation of SRPRB function has been linked to various human diseases, including neurodegenerative disorders and cancer. By studying SRPRB with this antibody, researchers can gain insights into the mechanisms underlying these conditions and potentially identify novel therapeutic targets for drug development.Overall, the SRPRB Polyclonal Antibody (CAB10591) is a valuable tool for researchers seeking to elucidate the role of SRPRB in cellular processes and disease pathogenesis. Its high reactivity and specificity make it a reliable choice for experiments aimed at uncovering the intricate mechanisms of protein transport and ER function.
Product Name:
SRPRB Rabbit Polyclonal Antibody
SKU:
CAB10591
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 57-271 of human SRPRB (NP_067026.3).
The protein encoded by this gene has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR). This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane.
Purification Method:
Affinity purification
Gene ID:
58477
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SRPRB Rabbit pAb (CAB10591) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
