The SRPR Polyclonal Antibody (CAB5939) is a valuable tool for researchers studying SRPR, a protein involved in controlling protein translocation and quality control in the endoplasmic reticulum. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting SRPR in human samples, making it an ideal choice for Western blot analysis.SRPR, also known as signal recognition particle receptor, plays a crucial role in ensuring proper protein folding and trafficking within cells. Dysregulation of SRPR function has been linked to various diseases, including neurodegenerative disorders and metabolic syndromes.
By targeting SRPR with this antibody, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially develop novel therapeutic strategies.Overall, the SRPR Polyclonal Antibody (CAB5939) is a reliable tool for investigating the role of SRPR in cellular processes and disease pathogenesis, making it a valuable asset for studies in cell biology, biochemistry, and biomedicine.
Product Name:
SRPR Rabbit Polyclonal Antibody
SKU:
CAB5939
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SRPR (NP_003130.2).
The gene encodes a subunit of the endoplasmic reticulum signal recognition particle receptor that, in conjunction with the signal recognition particle, is involved in the targeting and translocation of signal sequence tagged secretory and membrane proteins across the endoplasmic reticulum. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
6734
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SRPR antibody (CAB5939) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
