SRPK3 Antibody (PACO17170)
- SKU:
- PACO17170
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
SRPK3 Antibody (PACO17170)
The SRPK3 Polyclonal Antibody (PAC017170) is a valuable tool for researchers studying SRPK3, a serine-arginine protein kinase involved in alternative splicing regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding to the SRPK3 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in molecular biology and cancer research.
SRPK3 is a key player in the complex process of alternative splicing, which allows a single gene to produce multiple protein isoforms with distinct functions. Dysregulation of alternative splicing has been implicated in various diseases, including cancer, making SRPK3 a promising target for therapeutic interventions. By studying the role of SRPK3 in splicing regulation, researchers can gain valuable insights into disease mechanisms and potentially identify new targets for drug development.
| Antibody Name: | SRPK3 Antibody (PACO17170) |
| Antibody SKU: | PACO17170 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human SRPK3 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 8%SDS-PAGE,Lysate: 40 μg,,Primary antibody: PACO17170(SRPK3 Antibody) at dilution 1/300 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 3 minutes. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO17170(SRPK3 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | This gene encodes a protein kinase similar to a protein kinase which is specific for the SR (serine/arginine-rich domain) family of splicing factors. A highly similar protein has been shown to play a role in muscle development in mice. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Synonyms: | SRSF protein kinase 3 |
| UniProt Protein Function: | Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development (). |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a protein kinase similar to a protein kinase which is specific for the SR (serine/arginine-rich domain) family of splicing factors. A highly similar protein has been shown to play a role in muscle development in mice. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009] |
| UniProt Code: | Q9UPE1 |
| NCBI GenInfo Identifier: | 282847488 |
| NCBI Gene ID: | 26576 |
| NCBI Accession: | NP_001164231.1 |
| UniProt Secondary Accession: | Q9UPE1,Q13583, Q4F970, Q562F5, Q9UM62 |
| UniProt Related Accession: | Q9UPE1 |
| Molecular Weight: | 61,886 Da |
| NCBI Full Name: | SRSF protein kinase 3 isoform 2 |
| NCBI Synonym Full Names: | SRSF protein kinase 3 |
| NCBI Official Symbol: | SRPK3Â Â |
| NCBI Official Synonym Symbols: | MSSK1; STK23; MSSK-1Â Â |
| NCBI Protein Information: | SRSF protein kinase 3 |
| UniProt Protein Name: | SRSF protein kinase 3 |
| UniProt Synonym Protein Names: | Muscle-specific serine kinase 1; MSSK-1; Serine/arginine-rich protein-specific kinase 3; SR-protein-specific kinase 3; Serine/threonine-protein kinase 23 |
| Protein Family: | SRSF protein kinase |
| UniProt Gene Name: | SRPK3Â Â |
| UniProt Entry Name: |
| Antibodies |
| SRPK3 Antibody (PACO03848) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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