The SRP9 Polyclonal Antibody (CAB4124) is a valuable tool for researchers studying SRP9, a key component of the signal recognition particle (SRP) complex involved in protein targeting to the endoplasmic reticulum (ER). This polyclonal antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications.SRP9 is essential for the proper function of the SRP complex, which is responsible for directing newly synthesized proteins to the ER for proper folding and localization. Dysregulation of SRP9 function can lead to defects in protein trafficking and processing, contributing to various diseases such as neurodegenerative disorders and metabolic syndromes.
By targeting SRP9 with this polyclonal antibody, researchers can study the expression and localization of SRP9 in different cell types and tissues, providing insights into the mechanisms underlying protein targeting and processing. This antibody is a valuable tool for investigations in cell biology, molecular biology, and diseases related to protein misfolding and trafficking.
Product Name:
SRP9 Rabbit Polyclonal Antibody
SKU:
CAB4124
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-86 of human SRP9 (NP_003124.1).
Predicted to enable RNA binding activity and signal recognition particle binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane. Predicted to be located in cytosol. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting.
Purification Method:
Affinity purification
Gene ID:
6726
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of A-431 cells, using SRP9 antibody (CAB4124) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
