The SRP54 Polyclonal Antibody (CAB4126) is a valuable tool for researchers studying SRP54, a key protein involved in protein targeting and translocation to the endoplasmic reticulum. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the SRP54 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in the fields of cell biology and molecular biology.SRP54 is an essential component of the signal recognition particle (SRP) pathway, which is responsible for guiding ribosome-bound nascent proteins to the endoplasmic reticulum for membrane insertion or secretion.
Understanding the function of SRP54 is crucial for unraveling the mechanisms of protein targeting and translocation, making this antibody a valuable asset for research into cellular processes and protein trafficking. Researchers studying protein synthesis, cellular compartmentalization, and protein trafficking pathways will find the SRP54 Polyclonal Antibody to be a reliable tool for their investigations.
Product Name:
SRP54 Rabbit Polyclonal Antibody
SKU:
CAB4126
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 196-455 of human SRP54 (NP_001139754.1).
Enables several functions, including 7S RNA binding activity; endoplasmic reticulum signal peptide binding activity; and guanyl ribonucleotide binding activity. Contributes to GTPase activity. Involved in granulocyte differentiation and protein targeting to ER. Located in cytosol and nucleus. Part of signal recognition particle, endoplasmic reticulum targeting. Implicated in severe congenital neutropenia 8.
Purification Method:
Affinity purification
Gene ID:
6729
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SRP54 antibody (CAB4126) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
