The SRP19 Polyclonal Antibody (CAB6752) is a valuable tool for research involving SRP19, a key protein involved in protein targeting and translocation across the endoplasmic reticulum membrane. This antibody, produced in rabbits, shows high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the SRP19 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for studies in molecular biology and protein targeting mechanisms.SRP19 is a critical component of the signal recognition particle (SRP) complex, which plays a crucial role in directing newly synthesized proteins to the endoplasmic reticulum for proper localization and function.
Understanding the function and regulation of SRP19 is essential for deciphering the complex mechanisms of protein targeting and translocation, with implications for various cellular processes and disease states. This antibody provides researchers with a reliable tool for investigating the role of SRP19 in health and disease, offering new insights into molecular mechanisms and potential therapeutic targets.
Product Name:
SRP19 Rabbit Polyclonal Antibody
SKU:
CAB6752
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-144 of human SRP19 (NP_003126.1).
Enables 7S RNA binding activity. Contributes to ribosome binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition. Located in nucleolus. Part of signal recognition particle, endoplasmic reticulum targeting.
Purification Method:
Affinity purification
Gene ID:
6728
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using SRP19 Rabbit pAb (CAB6752) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
