The SFRPBP1 Polyclonal Antibody (CAB8856) is a valuable tool for researchers studying SFRPBP1, a protein involved in Wnt signaling pathway regulation and tumorigenesis. This antibody, derived from rabbits, exhibits high specificity for human samples and has been validated for use in Western blotting applications. By targeting the SFRPBP1 protein, researchers can effectively detect and analyze its expression in various cell types, making it an ideal resource for investigations in cancer biology and developmental biology.SFRPBP1, also known as secreted frizzled related protein binding protein 1, plays a crucial role in modulating the activity of Wnt signaling pathway components, ultimately impacting cell proliferation and differentiation processes.
Dysregulation of SFRPBP1 has been implicated in various cancers and developmental disorders, highlighting the importance of studying its function in disease pathogenesis. By further elucidating the role of SFRPBP1, researchers can gain insights into potential therapeutic targets for cancer treatment and developmental abnormalities.
Product Name:
SRFBP1 Rabbit Polyclonal Antibody
SKU:
CAB8856
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SRFBP1 (NP_689759.2).
Enables RNA binding activity. Predicted to be involved in maturation of SSU-rRNA. Predicted to be located in perinuclear region of cytoplasm. Predicted to be part of 90S preribosome. Predicted to be active in nucleus.
Purification Method:
Affinity purification
Gene ID:
153443
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SRFBP1 Rabbit pAb (CAB8856) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
