null

SRF Rabbit Polyclonal Antibody (CAB16718)

SKU:
CAB16718
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:SRF Rabbit Polyclonal Antibody
SKU:CAB16718
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human SRF (NP_003122.1).
Sequence:MLPT QAGA AAAL GRGS ALGG SLNR TPTG RPGG GGGT RGAN GGRV PGNG AGLG PGRL EREA AAAA ATTP APTA GALY SGSE GDSE SGEE EELG AERR GLKR SLSE MEIG MVVG GPEA SAAA TGGY GPVS GAVS GAKP GKKT RGRV KIKM EFID NKLR RYTT FSKR KTGI MKKA YELS TLTG TQVL LLVA SETG HVYT FATR KLQP MITS ETGK ALIQ TCLN SPDS PPRS DPTT DQRM SATG FEET DLTY QVSE SDSS GETK DTLK PAFT VTNL PGTT STIQ
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:MCM1; SRF
Positive Sample:Mouse liver,Mouse lung
Conjugate:Unconjugated
Cellular Localization:Nucleus.
Calculated MW:52kDa
Observed MW:68kDa

This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:6722
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using SRF Rabbit pAb (CAB16718) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.

Related Products