SRF Rabbit Polyclonal Antibody (CAB16718)
- SKU:
- CAB16718
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | SRF Rabbit Polyclonal Antibody |
SKU: | CAB16718 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human SRF (NP_003122.1). |
Sequence: | MLPT QAGA AAAL GRGS ALGG SLNR TPTG RPGG GGGT RGAN GGRV PGNG AGLG PGRL EREA AAAA ATTP APTA GALY SGSE GDSE SGEE EELG AERR GLKR SLSE MEIG MVVG GPEA SAAA TGGY GPVS GAVS GAKP GKKT RGRV KIKM EFID NKLR RYTT FSKR KTGI MKKA YELS TLTG TQVL LLVA SETG HVYT FATR KLQP MITS ETGK ALIQ TCLN SPDS PPRS DPTT DQRM SATG FEET DLTY QVSE SDSS GETK DTLK PAFT VTNL PGTT STIQ |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | MCM1; SRF |
Positive Sample: | Mouse liver,Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 52kDa |
Observed MW: | 68kDa |
This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 6722 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |