The SRD5A1 Polyclonal Antibody (CAB14787) is a valuable tool for researchers studying the SRD5A1 protein, which is involved in the biosynthesis of dihydrotestosterone (DHT), a hormone essential for male sexual development and function. This antibody, produced in rabbits, exhibits high specificity and reactivity towards human samples, making it an ideal choice for Western blot applications.SRD5A1 is a key enzyme in the androgen biosynthesis pathway, making it a target of interest in studies related to hormone regulation, prostate cancer, and other androgen-related disorders.
By binding to the SRD5A1 protein, this antibody enables accurate detection and analysis in various cell types, providing important insights into the role of SRD5A1 in normal physiology and disease states.Researchers in the fields of endocrinology, oncology, and reproductive biology will find the SRD5A1 Polyclonal Antibody to be a valuable resource in their investigations, ultimately contributing to a better understanding of the mechanisms underlying hormone-dependent diseases and potential therapeutic strategies.
Product Name:
SRD5A1 Rabbit Polyclonal Antibody
SKU:
CAB14787
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human SRD5A1 (NP_001038.1).
Steroid 5-alpha-reductase (EC 1.3.99.5) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). Also see SRD5A2 (MIM 607306).
Purification Method:
Affinity purification
Gene ID:
6715
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse skin, using SRD5A1 Rabbit pAb (CAB14787) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
