Src Rabbit Polyclonal Antibody (CAB11707)
- SKU:
- CAB11707
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Src Rabbit Polyclonal Antibody |
SKU: | CAB11707 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human Src (NP_005408.1). |
Sequence: | MGSN KSKP KDAS QRRR SLEP AENV HGAG GGAF PASQ TPSK PASA DGHR GPSA AFAP AAAE PKLF GGFN SSDT VTSP QRAG |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | ASV; SRC1; THC6; c-SRC; p60-Src; Src |
Positive Sample: | Jurkat,SH-SY5Y |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Mitochondrion inner membrane, Nucleus, cytoskeleton. |
Calculated MW: | 60kDa |
Observed MW: | 60kDa |
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 6714 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |