The SRC Polyclonal Antibody (CAB11707) is a valuable tool for researchers studying SRC, a tyrosine-protein kinase that plays a key role in cell signaling and regulation. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications. By binding to the SRC protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it essential for studies in signal transduction pathways, cancer biology, and drug development.SRC is a critical player in numerous cellular processes, including cell growth, differentiation, and survival. Dysregulation of SRC has been implicated in various diseases, including cancer, making it a promising target for therapeutic intervention.
By understanding the mechanisms of SRC activation and regulation, researchers can uncover new insights into disease pathogenesis and develop targeted treatments to combat these conditions.Overall, the SRC Polyclonal Antibody (CAB11707) is a powerful tool for researchers looking to investigate the role of SRC in cellular signaling and disease pathophysiology. Its high specificity and reactivity make it a valuable asset for studies aiming to unravel the complexities of SRC-mediated pathways and develop novel therapeutic strategies for cancer and other diseases.
Product Name:
Src Rabbit Polyclonal Antibody
SKU:
CAB11707
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human Src (NP_005408.1).
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6714
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Src Rabbit pAb (CAB11707) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
