The SRC Polyclonal Antibody (CAB0324) is a valuable tool for researchers studying SRC, a key protein involved in signal transduction pathways that regulate cell growth, differentiation, and survival. This antibody, produced in rabbits, shows high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the SRC protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an essential tool for investigations in cancer research, cell biology, and molecular biology.SRC is a non-receptor tyrosine kinase that plays a crucial role in various cellular processes, including cell proliferation, adhesion, migration, and survival.
Dysregulation of SRC activity has been implicated in the development and progression of numerous cancers, making it an attractive target for therapeutic intervention. Studying the function of SRC with the CAB0324 Polyclonal Antibody can provide valuable insights into the molecular mechanisms underlying cancer development and progression, ultimately leading to the identification of novel therapeutic targets for cancer treatment.
Product Name:
Src Rabbit Polyclonal Antibody
SKU:
CAB0324
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 410-536 of human Src (NP_005408.1).
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6714
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from SH-SY5Y cells, using Src Rabbit pAb (CAB0324) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
