The SRA1 Polyclonal Antibody (CAB16296) is a valuable tool for research involving SRA1, a protein involved in RNA processing and regulation. This antibody, raised in rabbits, is highly specific and reactive with human and mouse samples. It has been validated for use in various applications, including Western blot, immunofluorescence, and immunohistochemistry.SRA1, also known as steroid receptor RNA activator 1, plays a crucial role in modulating gene expression in response to steroid hormone signaling. It has been implicated in various cellular processes, including cell growth, differentiation, and apoptosis.
Research into SRA1 function is crucial for understanding its role in diseases such as cancer, metabolic disorders, and neurological conditions.By using the SRA1 Polyclonal Antibody, researchers can investigate the expression and localization of SRA1 in different cell types and tissues. This antibody enables precise detection and analysis of SRA1 protein levels, aiding in the study of its biological functions and potential therapeutic applications.
Product Name:
SRA1 Rabbit Polyclonal Antibody
SKU:
CAB16296
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SRA1 (NP_001030312.2).
Both long non-coding and protein-coding RNAs are transcribed from this gene, and they represent alternatively spliced transcript variants. This gene was initially defined as a non-coding RNA, which is a coactivator for several nuclear receptors (NRs) and is associated with breast cancer. It has now been found that this gene is involved in the regulation of many NR and non-NR activities, including metabolism, adipogenesis and chromatin organization. The long non-coding RNA transcripts interact with a variety of proteins, including the protein encoded by this gene. The encoded protein acts as a transcriptional repressor by binding to the non-coding RNA.
Purification Method:
Affinity purification
Gene ID:
10011
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using SRA1 Rabbit pAb (CAB16296) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
