The Squalene Synthase Polyclonal Antibody (CAB6229) is a valuable tool for researchers studying squalene synthase, an enzyme involved in the biosynthesis of cholesterol and other important molecules in the body. This antibody, raised in rabbits, is highly specific for human squalene synthase and has been validated for use in Western blot applications.Squalene synthase plays a crucial role in the cholesterol biosynthetic pathway, making it a promising target for therapies aimed at treating dyslipidemia and other related disorders. By detecting and analyzing squalene synthase expression in various cell types, this antibody can provide insights into the regulation of cholesterol synthesis and potential drug targets for cardiovascular diseases and metabolic disorders.
With its high reactivity and specificity, the Squalene Synthase Polyclonal Antibody (CAB6229) is an essential tool for researchers in the fields of biochemistry, molecular biology, and drug discovery. Its ability to detect squalene synthase protein levels will enable a better understanding of cholesterol metabolism and the development of novel therapeutic strategies.
Product Name:
SQS/FDFT1 Rabbit Polyclonal Antibody
SKU:
CAB6229
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human SQS/FDFT1 (NP_004453.3).
This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.
Purification Method:
Affinity purification
Gene ID:
2222
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using SQS/FDFT1 Rabbit pAb (CAB6229) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 1s.
