The SQS/FDFT1 Rabbit Monoclonal Antibody (CAB4651) is a valuable tool for researchers studying the SQS/FDFT1 protein, which is involved in the cholesterol biosynthesis pathway. This antibody, produced in rabbits, exhibits high specificity towards human samples and is ideal for use in Western blot applications to detect and analyze the SQS/FDFT1 protein in various cell types.SQS/FDFT1, also known as squalene synthase, is a key enzyme in the cholesterol biosynthesis pathway, making it a crucial target for research in lipid metabolism and related diseases such as atherosclerosis and metabolic disorders.
By using this antibody, researchers can gain valuable insights into the function and regulation of SQS/FDFT1, ultimately contributing to the development of potential therapeutic strategies for cholesterol-related disorders.
Product Name:
SQS/FDFT1 Rabbit Monoclonal Antibody
SKU:
CAB4651
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SQS/FDFT1 (P37268).
This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.
Purification Method:
Affinity purification
Gene ID:
2222
Clone Number:
ARC1077
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SQS/FDFT1 Rabbit mAb (CAB4651) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
