SPTLC2 Rabbit Polyclonal Antibody (CAB11716)
- SKU:
- CAB11716
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | SPTLC2 Rabbit Polyclonal Antibody |
SKU: | CAB11716 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 423-562 of human SPTLC2 (NP_004854.1). |
Sequence: | MKCI MGQD GTSL GKEC VQQL AENT RYFR RRLK EMGF IIYG NEDS PVVP LMLY MPAK IGAF GREM LKRN IGVV VVGF PATP IIES RARF CLSA AHTK EILD TALK EIDE VGDL LQLK YSRH RLVP LLDR PFDE TTYE ETED |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | LCB2; SPT2; HSN1C; LCB2A; NSAN1C; hLCB2a; SPTLC2 |
Positive Sample: | BxPC-3,U-87MG,293T,Mouse kidney,Mouse stomach |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Single-pass membrane protein. |
Calculated MW: | 63kDa |
Observed MW: | 58kDa |
This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.
Purification Method: | Affinity purification |
Gene ID: | 9517 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |