SPTLC1 Rabbit Polyclonal Antibody (CAB6750)
- SKU:
- CAB6750
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | SPTLC1 Rabbit Polyclonal Antibody |
SKU: | CAB6750 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 37-310 of human SPTLC1 (NP_006406.1). |
Sequence: | RLLF SKTY KLQE RSDL TVKE KEEL IEEW QPEP LVPP VPKD HPAL NYNI VSGP PSHK TVVN GKEC INFA SFNF LGLL DNPR VKAA ALAS LKKY GVGT CGPR GFYG TFDV HLDL EDRL AKFM KTEE AIIY SYGF ATIA SAIP AYSK RGDI VFVD RAAC FAIQ KGLQ ASRS DIKL FKHN DMAD LERL LKEQ EIED QKNP RKAR VTRR FIVV EGLY MNTG TICP LPEL VKLK YKYK ARIF LEES LSFG VLGE HGRG VTEH YGIN IDDI DLIS ANME NA |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | HSN1; LBC1; LCB1; SPT1; SPTI; ALS27; HSAN1; SPTLC1 |
Positive Sample: | SKOV3,MCF7,HepG2,Mouse kidney,Mouse lung,Mouse liver,Mouse thymus,Rat lung,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Single-pass membrane protein. |
Calculated MW: | 53kDa |
Observed MW: | 53kDa |
This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13.
Purification Method: | Affinity purification |
Gene ID: | 10558 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |