Alpha Fodrin Rabbit Polyclonal Antibody (CAB0160)
- SKU:
- CAB0160
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Alpha Fodrin Rabbit Polyclonal Antibody |
SKU: | CAB0160 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 950-1130 of human Alpha Fodrin (NP_001123910.1). |
Sequence: | REQA QSCR QQVA PTDD ETGK ELVL ALYD YQEK SPRE VTMK KGDI LTLL NSTN KDWW KVEV NDRQ GFVP AAYV KKLD PAQS ASRE NLLE EQGS IALR QEQI DNQT RITK EAGS VSLR MKQV EELY HSLL ELGE KRKG MLEK SCKK FMLF REAN ELQQ WINE KEAA LTSE EVGA DLEQ VEVL Q |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | DEE5; NEAS; EIEE5; SPTA2; Alpha Fodrin |
Positive Sample: | U-87MG,Jurkat,A-549,NIH/3T3,Mouse kidney,Rat spinal cord |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, cell cortex, cytoskeleton. |
Calculated MW: | 285kDa |
Observed MW: | 285kDa |
Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 6709 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |