The SPRY4 Polyclonal Antibody (CAB6263) is a valuable tool for researchers studying the SPRY4 protein, which is involved in regulating cell growth and proliferation. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to SPRY4, this antibody allows for the detection and analysis of the protein in various cell types, making it ideal for investigations in the fields of cell biology and cancer research.
SPRY4 is a crucial modulator of signaling pathways that control cell growth and differentiation, making it a key player in various physiological and pathological processes. Research into SPRY4 could lead to a better understanding of its role in cancer development, as well as potential therapeutic strategies that target this protein. By using the SPRY4 Polyclonal Antibody, researchers can further explore the functions of SPRY4 and its implications in disease progression.
Product Name:
SPRY4 Rabbit Polyclonal Antibody
SKU:
CAB6263
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-210 of human SPRY4 (NP_112226.2).
This gene encodes a member of a family of cysteine- and proline-rich proteins. The encoded protein is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. Activity of this protein impairs the formation of active GTP-RAS. Nucleotide variation in this gene has been associated with hypogonadotropic hypogonadism 17 with or without anosmia. Alternative splicing results in a multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
81848
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SPRY4 antibody (CAB6263) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
