The SPRR1A Polyclonal Antibody (CAB17535) is a high-quality antibody designed for research involving SPRR1A, a protein associated with epidermal development and keratinocyte differentiation. This rabbit polyclonal antibody is highly specific and reactive with human samples, making it a valuable tool for researchers studying skin biology and related disorders.SPRR1A, also known as Small Proline-Rich Protein 1A, is involved in the formation of the cornified cell envelope, a crucial process in skin barrier function. Abnormal expression of SPRR1A has been implicated in various skin conditions, making it a target of interest in dermatological research.
The SPRR1A Polyclonal Antibody binds specifically to SPRR1A protein, allowing for accurate detection and analysis in various experimental settings.This antibody is validated for use in Western blot applications, enabling researchers to study SPRR1A expression levels and localization in different cell types. By understanding the role of SPRR1A in skin physiology and pathology, researchers can gain insights into conditions such as psoriasis, atopic dermatitis, and wound healing, ultimately leading to the development of targeted therapeutic approaches.
Product Name:
SPRR1A Rabbit Polyclonal Antibody
SKU:
CAB17535
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-89 of human SPRR1A (NP_005978.2).
A structural constituent of skin epidermis. Involved in keratinocyte differentiation and peptide cross-linking. Located in cornified envelope.
Purification Method:
Affinity purification
Gene ID:
6698
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of Mouse stomach, using SPRR1A Rabbit pAb (CAB17535) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
