SPRED1 Rabbit Polyclonal Antibody (CAB14970)
- SKU:
- CAB14970
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | SPRED1 Rabbit Polyclonal Antibody |
SKU: | CAB14970 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 120-320 of human SPRED1 (NP_689807.1). |
Sequence: | IEDI SQGC PESK NEAE GADD LQAN EEDS SSSL VKDH LFQQ ETVV TSEP YRSS NIRP SPFE DLNA RRVY MQSQ ANQI TFGQ PGLD IQSR SMEY VQRQ ISKE CGSL KSQN RVPL KSIR HVSF QDED EIVR INPR DILI RRYA DYRH PDMW KNDL ERDD ADSS IQFS KPDS KKSD YLYS CGDE TKLS SPKD SVVF KTQP SSLK I |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | LGSS; NFLS; hSpred1; spred-1; PPP1R147; SPRED1 |
Positive Sample: | Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Membrane, Nucleus, Peripheral membrane protein, caveola. |
Calculated MW: | 50kDa |
Observed MW: | 50kDa |
The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS).
Purification Method: | Affinity purification |
Gene ID: | 161742 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |