The SPRED1 Polyclonal Antibody (CAB14970) is a valuable tool for researchers studying SPRED1, a key protein involved in various cellular processes, including cell proliferation and differentiation. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for use in Western blot applications. By binding to SPRED1, this antibody enables the detection and analysis of this protein in different cell types, allowing for in-depth investigation in fields such as cell biology and cancer research.SPRED1, also known as Sprouty-related, EVH1 domain-containing protein 1, is a crucial regulator of the Ras/MAPK signaling pathway, which plays a significant role in cell growth and development.
Dysregulation of this pathway has been associated with various diseases, including cancer and developmental disorders. Therefore, understanding the functions of SPRED1 is essential for unraveling its role in these conditions and potentially identifying new therapeutic targets.Overall, the SPRED1 Polyclonal Antibody is a reliable tool for researchers seeking to explore the functions and mechanisms of SPRED1 in cellular processes and diseases, with the ultimate goal of advancing our knowledge and finding new treatments.
Product Name:
SPRED1 Rabbit Polyclonal Antibody
SKU:
CAB14970
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 120-320 of human SPRED1 (NP_689807.1).
The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS).
Purification Method:
Affinity purification
Gene ID:
161742
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse brain, using SPRED1 Rabbit pAb (CAB14970) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
