The SPR Polyclonal Antibody (CAB11694) is a valuable tool for researchers studying SPR, a protein involved in various cellular processes such as signal transduction and immune responses. This polyclonal antibody, generated in rabbits, has been rigorously validated for use in Western blotting applications and exhibits high reactivity with human samples.SPR, also known as steroid receptor RNA activator, plays a critical role in mediating cellular responses to environmental stimuli, hormonal signaling, and stress. Its involvement in immune regulation and disease pathogenesis makes it an attractive target for investigation in fields such as immunology, cancer research, and drug development.
By utilizing the SPR Polyclonal Antibody (CAB11694), researchers can accurately detect and analyze SPR protein expression in different cell types and experimental conditions. This antibody enables detailed investigations into the function and regulation of SPR, providing valuable insights into its potential role as a therapeutic target for various diseases and disorders.
Product Name:
SPR Rabbit Polyclonal Antibody
SKU:
CAB11694
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-261 of human SPR (NP_003115.1).
This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
Purification Method:
Affinity purification
Gene ID:
6697
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SPR Rabbit pAb (CAB11694) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
