SPOP Rabbit Polyclonal Antibody (CAB12106)
- SKU:
- CAB12106
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | SPOP Rabbit Polyclonal Antibody |
SKU: | CAB12106 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 220-374 of human SPOP (NP_001007227.1). |
Sequence: | ARSP VFSA MFEH EMEE SKKN RVEI NDVE PEVF KEMM CFIY TGKA PNLD KMAD DLLA AADK YALE RLKV MCED ALCS NLSV ENAA EILI LADL HSAD QLKT QAVD FINY HASD VLET SGWK SMVV SHPH LVAE AYRS LASA QCPF LGPP RKRL KQS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | TEF2; BTBD32; NSDVS1; NSDVS2; NEDMACE; NEDMIDF; SPOP |
Positive Sample: | HeLa,HT-29 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus, Nucleus speckle. |
Calculated MW: | 42kDa |
Observed MW: | 42kDa |
This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein.
Purification Method: | Affinity purification |
Gene ID: | 8405 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |