SF1 Rabbit Polyclonal Antibody (CAB6424)
- SKU:
- CAB6424
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | SF1 Rabbit Polyclonal Antibody |
SKU: | CAB6424 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human SF1 (NP_973727.1). |
Sequence: | MATG ANAT PLDF PSKK RKRS RWNQ DTME QKTV IPGM PTVI PPGL TREQ ERAY IVQL QIED LTRK LRTG DLGI PPNP EDRS PSPE PIYN SEGK RLNT REFR TRKK LEEE RHNL ITEM VALN PDFK PPAD YKPP ATRV SDKV MIPQ DEYP EINF VGLL IGPR GNTL KNIE KECN AKIM IRGK GSVK EGKV GRKD GQML PGED EPLH ALVT ANTM ENVK KAVE QIRN ILKQ GIET PEDQ NDLR KMQL RELA RLNG TLRE DDNR ILRP WQSS ETRS ITNT TVCT |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | BBP; MBBP; ZFM1; ZNF162; D11S636; ZCCHC25; SF1 |
Positive Sample: | HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 68kDa |
Observed MW: | 68kDa |
This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence at the 3' splice site, together with the large subunit of U2 auxiliary factor (U2AF), and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre-mRNA retention and transcriptional repression. The encoded protein contains an N-terminal U2AF ligand motif, a central hnRNP K homology motif and quaking 2 region which bind a key branch-site adenosine within the branch point sequence, a zinc knuckles domain, and a C-terminal proline-rich domain. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 7536 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |