The SPK Polyclonal Antibody (CAB4852) is a powerful tool for researchers studying SPK, a protein involved in immune regulation and potentially pathway crosstalk. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it an excellent choice for experiments such as Western blot analysis. By targeting the SPK protein, this antibody allows for precise detection and characterization in a variety of cell types, making it ideal for investigations in immunology and cancer research.
SPK, also known as Signal Regulatory Protein Kappa, is known to play a critical role in immune response modulation and has been implicated in various diseases, including cancer and autoimmune disorders. Understanding the function and signaling pathways of SPK is essential for developing targeted therapies that can manipulate immune responses in these pathological conditions. The SPK Polyclonal Antibody is a valuable tool for researchers aiming to unravel the complexities of SPK biology and its implications in human health.
Product Name:
SPK Rabbit Polyclonal Antibody
SKU:
CAB4852
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-322 of human SPK (NP_060962.2).
This gene encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. The encoded protein may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Overexpression of this gene has been implicated in tumorigenesis. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
55872
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using SPK Rabbit pAb (CAB4852) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
