The SPIRE2 Polyclonal Antibody (CAB16582) is a powerful tool for research involving the SPIRE2 protein, a key regulator of actin cytoskeleton dynamics. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the SPIRE2 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for studies in cell biology and cytoskeletal dynamics.SPIRE2 plays a crucial role in the organization of actin filaments, which are essential for cell shape and movement.
Dysregulation of SPIRE2 has been implicated in various diseases, including cancer and neurological disorders. Research into SPIRE2 function is essential for understanding its role in these conditions and may lead to new therapeutic strategies targeting the actin cytoskeleton.By using the SPIRE2 Polyclonal Antibody, researchers can gain valuable insights into the function and regulation of SPIRE2, advancing our understanding of cell biology and offering potential new avenues for the development of therapeutic interventions.
Product Name:
SPIRE2 Rabbit Polyclonal Antibody
SKU:
CAB16582
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human SPIRE2 (NP_115827.1).
Predicted to enable actin binding activity. Involved in establishment of meiotic spindle localization; formin-nucleated actin cable assembly; and positive regulation of double-strand break repair. Predicted to be located in cytoskeleton; cytosol; and plasma membrane. Predicted to be active in cell cortex and cytoplasmic vesicle membrane. Predicted to colocalize with cleavage furrow.
Purification Method:
Affinity purification
Gene ID:
84501
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SPIRE2 Rabbit pAb (CAB16582) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
