The SPINK6 Polyclonal Antibody (PACO04253) is a crucial tool for researchers studying SPINK6, a serine protease inhibitor involved in skin barrier function and immune response regulation. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for various research applications, including Western blotting.SPINK6, also known as Serine Peptidase Inhibitor, Kazal type 6, is known for its role in protecting the skin from external pathogens and maintaining skin homeostasis.
It is also implicated in the regulation of inflammatory responses in the skin, suggesting its potential involvement in skin diseases and conditions.By targeting the SPINK6 protein, researchers can gain insights into its function and mechanisms of action in different cell types, aiding in the development of novel therapeutic strategies for skin disorders and immune-related conditions. The SPINK6 Polyclonal Antibody is a valuable tool for advancing research in dermatology, immunology, and related fields.
Antibody Name:
SPINK6 Antibody
Antibody SKU:
PACO04253
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human SPINK6.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
SPINK6: Serine protease inhibitor selective for kallikreins. Efficiently inhibits KLK4, KLK5, KLK6, KLK7, KLK12, KLK13 and KLK14. Doesn't inhibit KLK8.Protein type: Secreted, signal peptide; SecretedChromosomal Location of Human Ortholog: 5q32Cellular Component: extracellular regionMolecular Function: serine-type endopeptidase inhibitor activity
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is a Kazal-type serine protease inhibitor that acts on kallikrein-related peptidases in the skin. Two transcript variants the same protein have been found for this gene. [provided by RefSeq, Aug 2010]
