The SPINK1 Polyclonal Antibody (CAB13546) is a valuable tool for researchers studying the serine protease inhibitor Kazal-type 1 (SPINK1) protein. SPINK1 is known for its role in regulating proteolytic processes, particularly in the pancreas where it helps maintain a balance of digestive enzymes. This antibody, produced in rabbits, has been specifically developed for detection and analysis of the SPINK1 protein in human samples. It has been rigorously validated for use in Western blot applications, providing reliable and consistent results for researchers working in the fields of gastroenterology, pancreatic cancer, and digestive disorders.
Understanding the functions of SPINK1 is essential for gaining insights into pancreatic health and disease processes. By utilizing the SPINK1 Polyclonal Antibody, researchers can study the expression levels and localization of this important protein in various cell types, contributing to advancements in the diagnosis and treatment of conditions related to pancreatic dysfunction.
Product Name:
SPINK1 Rabbit Polyclonal Antibody
SKU:
CAB13546
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-79 of human SPINK1 (NP_003113.2).
The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis.
Purification Method:
Affinity purification
Gene ID:
6690
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of HeLa cells using SPINK1 antibody (CAB13546). Blue: DAPI for nuclear staining.
