The Spindlin-1 Polyclonal Antibody (CAB5853) is a valuable tool for researchers studying Spindlin-1, a protein involved in chromatin remodeling and gene regulation. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting Spindlin-1 in human samples, making it a reliable choice for various research applications, including Western blotting.Spindlin-1 is known to interact with histone proteins and play a role in epigenetic regulation, making it a key player in processes like cell differentiation and development.
Dysregulation of Spindlin-1 has been linked to various diseases, including cancer, making it a promising target for therapeutic intervention.By using the Spindlin-1 Polyclonal Antibody, researchers can gain valuable insights into the function and expression of Spindlin-1 in different cell types and contexts, furthering our understanding of its role in health and disease. This antibody is a valuable tool for studies in molecular biology, epigenetics, and cancer research.
Product Name:
SPIN1 Rabbit Polyclonal Antibody
SKU:
CAB5853
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-262 of human SPIN1 (NP_006708.2).
Enables methylated histone binding activity. Involved in positive regulation of Wnt signaling pathway; positive regulation of transcription, DNA-templated; and rRNA transcription. Located in cytosol and nucleus.
Purification Method:
Affinity purification
Gene ID:
10927
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using SPIN1 Rabbit pAb (CAB5853) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
