The SPIN3 Monoclonal Antibody (PACO36278) is a valuable tool for research involving SPIN3, a protein crucial for cell cycle regulation and DNA repair processes. This antibody, produced in mice, exhibits high specificity and sensitivity for detecting SPIN3 in human samples, making it a reliable choice for Western blot assays. By targeting the SPIN3 protein, this antibody enables researchers to study its impact on cellular processes in various cell types, offering valuable insights into cancer biology and DNA damage response mechanisms.SPIN3, also known as spindle assembly checkpoint regulator 3, plays a key role in ensuring accurate chromosome segregation during cell division, making it a potential target for cancer therapy.
Its involvement in DNA repair pathways further underscores its importance in maintaining genomic stability and preventing the accumulation of mutations that can lead to cancer development. Investigating the function of SPIN3 is essential for advancing our understanding of cancer biology and identifying novel therapeutic strategies to combat this disease.
Western blot. All lanes: SPIN3 antibody at 6µg/ml. Lane 1: A549 whole cell lysate. Lane 2: Hela whole cell lysate. Lane 3: A431 whole cell lysate. Lane 4: HepG2 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 30, 9 kDa. Observed band size: 30, 70 kDa.
Background:
Exhibits H3K4me3-binding activity.
Synonyms:
Spindlin-3 (Spindlin-like protein 3) (SPIN-3), SPIN3
UniProt Protein Function:
SPIN3: Belongs to the SPIN/STSY family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: Xp11.21Biological Process: gamete generation
