The SPHK2 Polyclonal Antibody (CAB3204) is a valuable tool for researchers studying sphingosine kinase 2 (SPHK2), an enzyme involved in sphingolipid metabolism and cell signaling pathways. This antibody, generated in rabbits, displays high specificity and reactivity towards human samples, making it ideal for use in Western blot experiments.SPHK2 is known to play a role in various cellular processes, including cell proliferation, survival, and migration, making it a key player in cancer biology and other diseases. By targeting SPHK2 with this antibody, researchers can better understand its function and potential as a therapeutic target in conditions such as cancer, inflammation, and autoimmune disorders.
With its ability to detect SPHK2 protein levels in different cell types, the SPHK2 Polyclonal Antibody (CAB3204) is a valuable tool for studies in cell biology, molecular biology, and drug discovery. By unlocking the mysteries of SPHK2, researchers can pave the way for new treatments and interventions in various disease states.
Product Name:
SPHK2 Rabbit Polyclonal Antibody
SKU:
CAB3204
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human SPHK2 (NP_001191088.1).
This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
56848
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse brain, using SPHK2 antibody (CAB3204).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
