SMOX Rabbit Polyclonal Antibody (CAB11677)
- SKU:
- CAB11677
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | SMOX Rabbit Polyclonal Antibody |
SKU: | CAB11677 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-544 of human SMOX (NP_787033.1). |
Sequence: | PRGG RWDE DEQW SVVV ECED CELI PADH VIVT VSLG VLKR QYTS FFRP GLPT EKVA AIHR LGIG TTDK IFLE FEEP FWGP ECNS LQFV WEDE AESH TLTY PPEL WYRK ICGF DVLY PPER YGHV LSGW ICGE EALV MEKC DDEA VAEI CTEM LRQF TGNP NIPK PRRI LRSA WGSN PYFR GSYS YTQV GSSG ADVE KLAK PLPY TESS KTAP MQVL FSGE ATHR KYYS TTHG ALLS GQRE AARL I |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | PAO; SMO; PAO1; PAOH; PAO-1; PAOH1; C20orf16; SMOX |
Positive Sample: | 293T,C2C12,Rat testis,Rat pancreas |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 62kDa |
Observed MW: | 62kDa |
Polyamines are ubiquitous polycationic alkylamines which include spermine, spermidine, putrescine, and agmatine. These molecules participate in a broad range of cellular functions which include cell cycle modulation, scavenging reactive oxygen species, and the control of gene expression. These molecules also play important roles in neurotransmission through their regulation of cell-surface receptor activity, involvement in intracellular signalling pathways, and their putative roles as neurotransmitters. This gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermadine and secondarily produces hydrogen peroxide. Multiple transcript variants encoding different isoenzymes have been identified for this gene, some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates. The characterized isoenzymes have distinctive biochemical characteristics and substrate specificities, suggesting the existence of additional levels of complexity in polyamine catabolism.
Purification Method: | Affinity purification |
Gene ID: | 54498 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |