SPDEF Rabbit Polyclonal Antibody (CAB6747)
- SKU:
- CAB6747
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | SPDEF Rabbit Polyclonal Antibody |
SKU: | CAB6747 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-335 of human SPDEF (NP_036523.1). |
Sequence: | MGSA SPGL SSVS PSHL LLPP DTVS RTGL EKAA AGAV GLER RDWS PSPP ATPE QGLS AFYL SYFD MLYP EDSS WAAK APGA SSRE EPPE EPEQ CPVI DSQA PAGS LDLV PGGL TLEE HSLE QVQS MVVG EVLK DIET ACKL LNIT ADPM DWSP SNVQ KWLL WTEH QYRL PPMG KAFQ ELAG KELC AMSE EQFR QRSP LGGD VLHA HLDI WKSA AWMK ERTS PGAI HYCA STSE ESWT DSEV DSSC SGQP IHLW QFLK ELLL KPHS YGRF IRWL NKEK GIFK IEDS AQVA RLWG IRKN RPAM NYDK LSRS IRQY YKKG IIRK PDIS QRLV YQFV HPI |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PDEF; bA375E1.3; SPDEF |
Positive Sample: | HT-29 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 38kDa |
Observed MW: | 50kDa |
The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 25803 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |