The SPCS2 Polyclonal Antibody (PAC012428) is a valuable tool for researchers studying the SPCS2 protein, a key component of the signal peptidase complex involved in protein processing and secretion. This rabbit-raised antibody is highly specific for human samples and is validated for use in Western blot applications, allowing for precise detection and analysis of SPCS2 in various cell types.SPCS2 is essential for the proper functioning of the signal peptidase complex, which plays a critical role in post-translational protein processing and secretion. Dysregulation of SPCS2 has been implicated in various diseases, including cancer and neurodegenerative disorders, making it a promising target for therapeutic interventions.
By studying the activity of SPCS2, researchers can gain valuable insights into the molecular mechanisms underlying these diseases and potentially develop novel treatment strategies.Overall, the SPCS2 Polyclonal Antibody is an indispensable tool for researchers working in the fields of molecular biology, cell biology, and disease research. Its high specificity and reliability make it an ideal choice for investigating the role of SPCS2 in cellular processes and disease pathogenesis.
signal peptidase complex subunit 2 homolog (S. cerevisiae);SPCS2;KIAA0102;MGC117366 ;
UniProt Protein Function:
SPCS2: Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Belongs to the SPCS2 family.Protein type: EC 3.4.-.-; Protease; Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 11q13.4Cellular Component: endoplasmic reticulum membrane; integral to membrane; signal peptidase complexMolecular Function: peptidase activityBiological Process: protein targeting to ER; signal peptide processing
