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SPCS1 Antibody (PACO12427)

SKU:
PACO12427
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€459
Frequently bought together:

Description

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SPCS1 Antibody (PACO12427)

The SPCS1 Polyclonal Antibody (PACO12427) is a valuable tool for researchers studying the SPCS1 protein, which plays a key role in cell cycle progression and division. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the SPCS1 protein, this antibody enables accurate detection and analysis in a range of cell types, making it an essential component for studies in cell biology and cancer research.SPCS1, also known as signal peptidase complex subunit 1, is involved in the processing and cleavage of signal peptides during protein synthesis and secretion. Dysregulation of SPCS1 has been linked to various diseases, including cancer, where aberrant cell proliferation and survival are observed.

Investigating the function and regulation of SPCS1 is essential for understanding its role in disease pathogenesis and for developing targeted therapies to modulate its activity.In conclusion, the SPCS1 Polyclonal Antibody (PACO12427) is a valuable research tool for scientists exploring the functions of the SPCS1 protein in cell biology and cancer. Its high reactivity and specificity make it a reliable choice for Western blot applications, aiding in the accurate detection and analysis of SPCS1 in various experimental settings. Unlock the potential of SPCS1 research with this reliable and versatile antibody.

Antibody Name:SPCS1 Antibody (PACO12427)
Antibody SKU:PACO12427
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human SPCS1
Form:Liquid
Storage Buffer:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity Purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:signal peptidase complex subunit 1 homolog (S. cerevisiae);SPCS1;HSPC033;SPC1;SPC12;YJR010C-A ;
UniProt Protein Function:SPCS1: Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Belongs to the SPCS1 family.
UniProt Protein Details:

Protein type:Protease; Endoplasmic reticulum; Amino Acid Metabolism - lysine degradation; Cofactor and Vitamin Metabolism - biotin; Membrane protein, multi-pass; EC 3.4.-.-; Membrane protein, integral

Chromosomal Location of Human Ortholog: 3p21.1

Cellular Component: endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane; signal peptidase complex

Molecular Function:peptidase activity; protein binding

Biological Process: protein targeting to ER; SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process; signal peptide processing; translation; gene expression; proteolysis; regulation of insulin secretion

UniProt Code:Q9Y6A9
NCBI GenInfo Identifier:557952606
NCBI Gene ID:28972
NCBI Accession:Q9Y6A9.4
UniProt Secondary Accession:Q9Y6A9,Q9BVW1, B3KNF8,
UniProt Related Accession:Q9Y6A9
Molecular Weight:169
NCBI Full Name:Signal peptidase complex subunit 1
NCBI Synonym Full Names:signal peptidase complex subunit 1 homolog (S. cerevisiae)
NCBI Official Symbol:SPCS1  
NCBI Official Synonym Symbols:SPC1; SPC12; HSPC033; YJR010C-A  
NCBI Protein Information:signal peptidase complex subunit 1; SPase 12 kDa subunit; signal peptidase 12kDa; microsomal signal peptidase 12 kDa subunit
UniProt Protein Name:Signal peptidase complex subunit 1
UniProt Synonym Protein Names:Microsomal signal peptidase 12 kDa subunit; SPase 12 kDa subunit
Protein Family:Signal peptidase complex
UniProt Gene Name:SPCS1  
UniProt Entry Name:SPCS1_HUMAN

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