The SPC24 Polyclonal Antibody (CAB16601) is a versatile tool for researchers studying SPC24, a key component of the NDC80 complex involved in mitosis and cell division. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blotting applications. By binding specifically to SPC24 protein, this antibody facilitates its detection and analysis in various cell types, making it an essential reagent for studies in cell biology and cancer research.
SPC24 is essential for proper chromosome segregation during mitosis, playing a crucial role in ensuring accurate cell division. Dysregulation of SPC24 has been implicated in various diseases, including cancer, making it a promising target for therapeutic interventions. By understanding the function of SPC24, researchers can gain insights into the mechanisms underlying cell division and potentially develop novel treatments for cancer and other proliferative disorders.
Product Name:
SPC24 Rabbit Polyclonal Antibody
SKU:
CAB16601
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-197 of human SPC24 (NP_872319.1).
Predicted to be involved in cell division. Located in nucleolus and nucleoplasm. Part of Ndc80 complex.
Purification Method:
Affinity purification
Gene ID:
147841
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of HeLa, using SPC24 antibody (CAB16601) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
