The SPATA5L1 Polyclonal Antibody (PAC020592) is a valuable tool for researchers studying SPATA5L1, a protein involved in spermatogenesis and fertility. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the SPATA5L1 protein, this antibody enables accurate detection and analysis in various cell types, making it an ideal choice for investigations in reproductive biology and fertility research.
SPATA5L1 is known for its role in male fertility and spermatogenesis, making it a key target for studies on infertility and reproductive health. Understanding the function of SPATA5L1 is essential for uncovering potential therapies for male infertility and other reproductive disorders. By utilizing the SPATA5L1 Polyclonal Antibody, researchers can gain valuable insights into the mechanisms underlying spermatogenesis and fertility, paving the way for advancements in reproductive medicine.
Antibody Name:
SPATA5L1 Antibody (PACO20592)
Antibody SKU:
PACO20592
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:5000, IHC:1:10-1:50
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human SPATA5L1
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO20592(SPATA5L1 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
SPATA5L1 (spermatogenesis-associated protein 5-like protein 1) is a 753 amino acid, protein belonging to the AAA ATPase family and AFG2 subfamily. Single nucleotide polymorphisms (SNPs) present in SPATA5L1 at the glycine amidinotransferase (GATM)-SPATA5L1 locus have been found to correlate with glomerular filtration rate (GFR), having significant implications for kidney disease research. SPATA5L1 localizes to cytoplasm and exists as three alternatively spliced isoforms.
Synonyms:
spermatogenesis associated 5-like 1
UniProt Protein Function:
SPATA5L1: Belongs to the AAA ATPase family. AFG2 subfamily. 3 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 15q21.1Cellular Component: cytoplasmMolecular Function: ATP binding
