SPATA17 Antibody (PACO15064)
- SKU:
- PACO15064
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | SPATA17 Antibody (PACO15064) |
| Antibody SKU: | PACO15064 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Fusion protein of human SPATA17 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO15064(SPATA17 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
 | Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human liver cancer tissue, Primary antibody: PACO15064(SPATA17 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO15064(SPATA17 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | Spata17 gene, which called MSRG11, by digital differential display of ESTs found only in testis. The deduced 292-amino acid, protein was considered to be a member of the family of calmodulin (CaM)-binding proteins because it contained 3 short CaM-binding motifs containing conserved ile and gln residues (IQ motif). Spata17 protein was most abundant in the cytoplasm of round spermatids and elongating spermatids within seminiferous tubules of the adult testis. Expression gradually decreased in the manipulated testis of animals that underwent experimental unilateral cryptorchidism. Transient transfection experiments with a Spata17 expression construct in cultured spermatogonia GC-1 cells indicated that Spata17 accelerated apoptosis in a dose-dependent manner. |
| Synonyms: | spermatogenesis associated 17 |
| UniProt Protein Function: | SPATA17: Chromosomal Location of Human Ortholog: 1q41Cellular Component: cytoplasmMolecular Function: calmodulin binding |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q96L03 |
| NCBI GenInfo Identifier: | 20270345 |
| NCBI Gene ID: | 128153 |
| NCBI Accession: | NP_620151.1 |
| UniProt Secondary Accession: | Q96L03,A5D6N2 |
| UniProt Related Accession: | Q96L03 |
| Molecular Weight: | 43,499 Da |
| NCBI Full Name: | spermatogenesis-associated protein 17 |
| NCBI Synonym Full Names: | spermatogenesis associated 17 |
| NCBI Official Symbol: | SPATA17Â Â |
| NCBI Official Synonym Symbols: | IQCH; MSRG11; MSRG-11Â Â |
| NCBI Protein Information: | spermatogenesis-associated protein 17; IQ motif containing H; spermatogenesis-related protein 11 |
| UniProt Protein Name: | Spermatogenesis-associated protein 17 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Spermatogenesis-associated protein |
| UniProt Gene Name: | SPATA17Â Â |
| UniProt Entry Name: | SPT17_HUMAN |
Related Products
HMGB3 Rabbit Polyclonal Antibody (CAB15064)
€139 - €419
