SPARC Rabbit Polyclonal Antibody (CAB14494)
- SKU:
- CAB14494
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | SPARC Rabbit Polyclonal Antibody |
SKU: | CAB14494 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-303 of human SPARC (NP_003109.1). |
Sequence: | APQQ EALP DETE VVEE TVAE VTEV SVGA NPVQ VEVG EFDD GAEE TEEE VVAE NPCQ NHHC KHGK VCEL DENN TPMC VCQD PTSC PAPI GEFE KVCS NDNK TFDS SCHF FATK CTLE GTKK GHKL HLDY IGPC KYIP PCLD SELT EFPL RMRD WLKN VLVT LYER DEDN NLLT EKQK LRVK KIHE NEKR LEAG DHPV ELLA RDFE KNYN MYIF PVHW QFGQ LDQH PIDG YLSH TELA PLRA PLIP MEHC TTRF FETC DLDN DKYI ALDE WAGC FGIK QKDI DKDL VI |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:100 IF/ICC,1:50 - 1:100 |
Synonyms: | ON; ONT; OI17; BM-40; SPARC |
Positive Sample: | A375 |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted, basement membrane, extracellular matrix, extracellular space. |
Calculated MW: | 35kDa |
Observed MW: | 35kDa |
This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 6678 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |