SPANXD Antibody (PACO37998)
- SKU:
- PACO37998
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
SPANXD Antibody (PACO37998)
The SPANXD Polyclonal Antibody (PAC037998) is a valuable tool for researchers studying SPANXD, a protein involved in immune regulation and inflammatory response. This antibody, developed using rabbits as the host, demonstrates high reactivity with human samples and is validated for Western blot applications. By binding to the SPANXD protein, researchers can accurately detect and analyze its expression in various cell types, making it an ideal choice for studies related to immunology and cancer research.
SPANXD, also referred to as an immune modulator, plays a key role in maintaining immune balance by regulating inflammatory processes and modulating immune responses. Its involvement in immune function makes it a promising target for investigating diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the function of SPANXD is critical for developing therapies that can manipulate immune responses in these disease contexts.
| Antibody Name: | SPANXD Antibody (PACO37998) |
| Antibody SKU: | PACO37998 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Sperm protein associated with the nucleus on the X chromosome D protein (1-97AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human testis tissue using PACO37998 at dilution of 1:100. |
| Synonyms: | Sperm protein associated with the nucleus on the X chromosome D (Cancer/testis antigen 11.4) (CT11.4) (Nuclear-associated protein SPAN-Xd) (SPANX-D) (SPANX family member D), SPANXD, SPANXE |
| UniProt Protein Function: | SPANXD: Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a sperm protein that is associated with the nucleus but, although a role in spermatogenesis is suggested, the specific function of this family member has not yet been determined. [provided by RefSeq, Jul 2008]Protein type: Cancer Testis Antigen (CTA)Chromosomal Location of Human Ortholog: Xq27.1Cellular Component: cytoplasm; nucleus |
| UniProt Protein Details: | |
| NCBI Summary: | Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a sperm protein that is associated with the nucleus but, although a role in spermatogenesis is suggested, the specific function of this family member has not yet been determined. Polymorphisms in this gene may be associated with prostate cancer susceptibility. [provided by RefSeq, Apr 2014] |
| UniProt Code: | Q9BXN6 |
| NCBI GenInfo Identifier: | 14192939 |
| NCBI Gene ID: | 64648 |
| NCBI Accession: | NP_115793.1 |
| UniProt Secondary Accession: | Q9BXN6,Q5JWI1 |
| UniProt Related Accession: | Q9BXN6 |
| Molecular Weight: | 11,029 Da |
| NCBI Full Name: | sperm protein associated with the nucleus on the X chromosome D |
| NCBI Synonym Full Names: | SPANX family, member D |
| NCBI Official Symbol: | SPANXDÂ Â |
| NCBI Official Synonym Symbols: | CT11.4; SPANXE; SPANX-C; SPANX-D; SPANX-E; dJ171K16.1Â Â |
| NCBI Protein Information: | sperm protein associated with the nucleus on the X chromosome D; SPANX family, member E; cancer/testis antigen 11.4; nuclear-associated protein SPAN-Xd; nuclear-associated protein SPAN-Xe; cancer/testis antigen family 11, member 4; sperm protein associated with the nucleus, X chromosome, family member D; sperm protein associated with the nucleus, X chromosome, family member E |
| UniProt Protein Name: | Sperm protein associated with the nucleus on the X chromosome D |
| UniProt Synonym Protein Names: | Cancer/testis antigen 11.4; CT11.4; Nuclear-associated protein SPAN-Xd; SPANX-D; SPANX family member D |
| Protein Family: | Sperm protein associated with the nucleus on the X chromosome |
| UniProt Gene Name: | SPANXDÂ Â |
| UniProt Entry Name: | SPNXD_HUMAN |
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