The SPANXC Antibody (PAC012418) is a polyclonal antibody specifically designed for research involving SPANXC, a cancer/testis antigen that is known to be highly expressed in certain cancers. This antibody, generated in rabbits, is highly reactive with human samples and has been validated for use in various applications, including immunohistochemistry and Western blotting. It specifically targets the SPANXC protein, allowing for the detection and analysis of SPANXC expression in different cell types.
SPANXC is a promising target for cancer research due to its restricted expression pattern in normal tissues and its overexpression in multiple tumor types. By studying the role of SPANXC in cancer development and progression, researchers can gain valuable insights into potential therapeutic strategies and diagnostic markers for various types of cancer. The SPANXC Antibody provides a valuable tool for researchers interested in exploring the significance of SPANXC in cancer biology.
SPANX family, member C;SPANXC;C;CT11.3;CTp11;SPANX-C ;
UniProt Protein Function:
SPANXC: Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family, which is located in a gene cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a protein that localizes to the nucleus and is expressed in highly metastatic cell lines, making the protein a potential diagnostic and prognostic marker. The protein belongs to a family of cancer/testis antigens and represents a potential target for cancer immunotherapy. [provided by RefSeq, Jul 2008]Protein type: Cancer Testis Antigen (CTA)Chromosomal Location of Human Ortholog: Xq27.1Cellular Component: cytoplasm; nucleus
