SPAG6 Rabbit Polyclonal Antibody (CAB3088)
- SKU:
- CAB3088
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | SPAG6 Rabbit Polyclonal Antibody |
SKU: | CAB3088 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 180-290 of human SPAG6 (NP_758442.1). |
Sequence: | EIAL KRIA ASAL SDIA KHSP ELAQ TVVD AGAV AHLA QMIL NPDA KLKH QILS ALSQ VSKH SVDL AEMV VEAE IFPV VLTC LKDK DEYV KKNA STLI REIA KHTP ELSQ LVV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | pf16; CT141; FAP194; CFAP194; Repro-SA-1; SPAG6 |
Positive Sample: | Jurkat,PC-3 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell projection, Cytoplasm, cilium, cytoskeleton, flagellum. |
Calculated MW: | 55kDa |
Observed MW: | 55kDa |
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 9576 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |